Anti-VDR Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-VDR Polyclonal Antibody

品牌:solarbio | 货号:K006855P

英文名称 Anti-VDR Polyclonal Antibody
宿主 Rabbit
别名 NR1I1;PPP1R163
应用 IHC
稀释比例 IHC 1:20-100.
交叉反应 Human Mouse Rat
蛋白分子量 48kDa
Gene ID 7421
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human VDR
性状 液体
Public Immunogen Range Recombinant protein of human VDR
Subcellular Locations Nucleus
Swiss Prot P11473
克隆类型 Polyclonal Antibody
背景资料 This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins.