Anti-KPNA6 Polyclonal Antibody
品牌：solarbio | 货号：K005205P
| 英文名称 | Anti-KPNA6 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | IPOA7;KPNA7 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 60kDa |
| Gene ID | 23633 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human KPNA6 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human KPNA6 |
| Subcellular Locations | Cytosol Nucleus |
| Swiss Prot | O60684 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. |