Anti-DPM1 Polyclonal Antibody
品牌：solarbio | 货号：K005443P
| 英文名称 | Anti-DPM1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CDGIE;MPDS |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 30kDa |
| Gene ID | 8813 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human DPM1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human DPM1 |
| Subcellular Locations | Endoplasmic reticulum |
| Swiss Prot | O60762 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants. |