Anti-NSMCE2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-NSMCE2 Polyclonal Antibody

品牌:solarbio | 货号:K106963P

英文名称 Anti-NSMCE2 Polyclonal Antibody
宿主 Rabbit
别名 C8orf36;E3 SUMO protein ligase NSE2;hMMS21;MMS21;MMS21 homolog;Non SMC element 2 homolog;NSE2;NSMCE2
应用 WB
稀释比例 WB 1:8000-12000.
交叉反应 Human
蛋白分子量 28kDa
Gene ID 286053
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human NSMCE2
性状 液体
Public Immunogen Range Recombinant protein of human NSMCE2
Subcellular Locations Nucleus?
Swiss Prot Q96MF7
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance.?