Anti-NSMCE2 Polyclonal Antibody
品牌：solarbio | 货号：K106963P
| 英文名称 | Anti-NSMCE2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | C8orf36;E3 SUMO protein ligase NSE2;hMMS21;MMS21;MMS21 homolog;Non SMC element 2 homolog;NSE2;NSMCE2 |
| 应用 | WB |
| 稀释比例 | WB 1:8000-12000. |
| 交叉反应 | Human |
| 蛋白分子量 | 28kDa |
| Gene ID | 286053 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human NSMCE2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human NSMCE2 |
| Subcellular Locations | Nucleus? |
| Swiss Prot | Q96MF7 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance.? |