Anti-ITGA5 Polyclonal Antibody
品牌:solarbio | 货号:K106885P
| 英文名称 | Anti-ITGA5 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD49e;FNRA;VLA-5;VLA5A;integrin alpha-5 |
| 应用 | IHC |
| 稀释比例 | IHC 1:20-50. |
| 交叉反应 | Human |
| 蛋白分子量 | 115kDa |
| Gene ID | 3678 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human ITGA5 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human ITGA5 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P08648 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. |