Anti-ITGA5 Polyclonal Antibody
品牌:solarbio | 货号:K106885P
英文名称 |
Anti-ITGA5 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CD49e;FNRA;VLA-5;VLA5A;integrin alpha-5 |
应用 |
IHC |
稀释比例 |
IHC 1:20-50. |
交叉反应 |
Human |
蛋白分子量 |
115kDa |
Gene ID |
3678 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human ITGA5 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human ITGA5 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P08648 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. |