Anti-AKR1C2 Polyclonal Antibody
品牌:solarbio | 货号:K106743P
英文名称 |
Anti-AKR1C2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
BABP;DD;DD2;DDH2;HAKRD;MCDR2;TDD |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
37kDa |
Gene ID |
1646 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human AKR1C2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human AKR1C2 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P52895 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene. |