Anti-NQO1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-NQO1 Polyclonal Antibody

品牌:solarbio | 货号:K106519P

英文名称 Anti-NQO1 Polyclonal Antibody
宿主 Rabbit
别名 DHQU;DIA4;DTD;NMOR1;NMORI;QR1
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量 27kDa
Gene ID 1728
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human NQO1
性状 液体
Public Immunogen Range A synthetic peptide of human NQO1
Subcellular Locations Cytoplasm Cell membrane
Swiss Prot P15559
克隆类型 Polyclonal Antibody
背景资料 This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein’s enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer’s disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.