Anti-EIF4G2 Polyclonal Antibody
品牌：solarbio | 货号：K007419P
| 英文名称 | Anti-EIF4G2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | P97;AAG1;DAP5;NAT1 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 103kDa |
| Gene ID | 1982 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human EIF4G2 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human EIF4G2 |
| Subcellular Locations | Cytosol |
| Swiss Prot | P78344 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. |