Anti-SMARCA4 Polyclonal Antibody
品牌：solarbio | 货号：K007391P
| 英文名称 | Anti-SMARCA4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BRG1;SNF2;SWI2;MRD16;RTPS2;BAF190;SNF2L4;SNF2LB;hSNF2b;BAF190A |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 185kDa |
| Gene ID | 6597 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human SMARCA4 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human SMARCA4 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | P51532 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. |