Anti-EIF2S1 Polyclonal Antibody
品牌：solarbio | 货号：K007364P
| 英文名称 | Anti-EIF2S1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | EIF2;EIF-2;EIF2A;EIF-2A;EIF-2alpha |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:30-150. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 36kDa |
| Gene ID | 1965 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human EIF2S1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human EIF2S1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P05198 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]). |