Anti-RAB3IP Polyclonal Antibody
品牌：solarbio | 货号：K007343P
| 英文名称 | Anti-RAB3IP Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | RABIN3;RABIN8 |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 53kDa |
| Gene ID | 117177 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human RAB3IP |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human RAB3IP |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q96QF0 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. |