Anti-CRK Polyclonal Antibody
品牌:solarbio | 货号:K007000P
英文名称 |
Anti-CRK Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
p38;CRKII |
应用 |
IHC |
稀释比例 |
IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
34kDa |
Gene ID |
1398 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human CRK |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human CRK |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P46108 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. |