Anti-CLPS Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CLPS Polyclonal Antibody

品牌:solarbio | 货号:K006992P

英文名称 Anti-CLPS Polyclonal Antibody
宿主 Rabbit
别名 Colipase
应用 IHC
稀释比例 IHC 1:50-200.
交叉反应 Human
蛋白分子量 12kDa
Gene ID 1208
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human CLPS
性状 液体
Public Immunogen Range Recombinant protein of human CLPS
Subcellular Locations Cytoplasm
Swiss Prot P04118
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.?