Anti-CLPS Polyclonal Antibody
品牌:solarbio | 货号:K006992P
英文名称 |
Anti-CLPS Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
Colipase |
应用 |
IHC |
稀释比例 |
IHC 1:50-200. |
交叉反应 |
Human |
蛋白分子量 |
12kDa |
Gene ID |
1208 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human CLPS |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human CLPS |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P04118 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.? |