Anti-DDB2 Polyclonal Antibody
品牌：solarbio | 货号：K006726P
| 英文名称 | Anti-DDB2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | XPE;DDBB;UV-DDB2 |
| 应用 | IHC |
| 稀释比例 | IHC 1:30-150. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 48kDa |
| Gene ID | 1643 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human DDB2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human DDB2 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q92466 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. |