Anti-IL21R Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-IL21R Polyclonal Antibody

品牌:solarbio | 货号:K006658P

英文名称 Anti-IL21R Polyclonal Antibody
宿主 Rabbit
别名 NILR;CD360
应用 IHC
稀释比例 IHC 1:25-100.
交叉反应 Human
蛋白分子量 59kDa
Gene ID 50615
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human IL21R
性状 液体
Public Immunogen Range Recombinant protein of human IL21R
Subcellular Locations Cytoplasm
Swiss Prot Q9HBE5
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.