Anti-CFL2 Polyclonal Antibody
品牌:solarbio | 货号:K005619P
英文名称 |
Anti-CFL2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
NEM7 |
应用 |
WB IF |
稀释比例 |
WB 1:500-2000. IF 1:50-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
19kDa |
Gene ID |
1073 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human CFL2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human CFL2 |
Subcellular Locations |
Cytoplasm Nucleus matrix cytoskeleton |
Swiss Prot |
Q9Y281 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. |