Anti-CAST Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CAST Polyclonal Antibody

品牌:solarbio | 货号:K005356P

英文名称 Anti-CAST Polyclonal Antibody
宿主 Rabbit
别名 BS-17;PLACK
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse Rat
蛋白分子量 77kDa
Gene ID 831
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CAST
性状 液体
Public Immunogen Range A synthetic peptide of human CAST
Subcellular Locations Cytosol Endoplasmic reticulum
Swiss Prot P20810
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.