Anti-CAST Polyclonal Antibody
品牌:solarbio | 货号:K005356P
英文名称 |
Anti-CAST Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
BS-17;PLACK |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
77kDa |
Gene ID |
831 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human CAST |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human CAST |
Subcellular Locations |
Cytosol Endoplasmic reticulum |
Swiss Prot |
P20810 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. |