Anti-TCEB2 Polyclonal Antibody
品牌：solarbio | 货号：K003941P
| 英文名称 | Anti-TCEB2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ELOB;TCEB2;SIII; |
| 应用 | WB IP |
| 稀释比例 | WB 1:500-2000. IP 1:20-50. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 13kDa |
| Gene ID | 6923 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human TCEB2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human TCEB2 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q15370 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13. |