Anti-CD97 Polyclonal Antibody
品牌:solarbio | 货号:K003697P
| 英文名称 | Anti-CD97 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ADGRE5;CD97;TM7LN1; |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-2000. IHC 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 92kDa |
| Gene ID | 976 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CD97 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CD97 |
| Subcellular Locations | Cell membrane Multi-pass membrane protein Secreted extracellular space |
| Swiss Prot | P48960 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. |