Anti-CD97 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CD97 Polyclonal Antibody

品牌:solarbio | 货号:K003697P

英文名称 Anti-CD97 Polyclonal Antibody
宿主 Rabbit
别名 ADGRE5;CD97;TM7LN1;
应用 WB IHC
稀释比例 WB 1:200-2000. IHC 1:50-100.
交叉反应 Human Mouse Rat
蛋白分子量 92kDa
Gene ID 976
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human CD97
性状 液体
Public Immunogen Range Recombinant protein of human CD97
Subcellular Locations Cell membrane Multi-pass membrane protein Secreted extracellular space
Swiss Prot P48960
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.