Anti-CD97 Polyclonal Antibody
品牌:solarbio | 货号:K003697P
英文名称 |
Anti-CD97 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ADGRE5;CD97;TM7LN1; |
应用 |
WB IHC |
稀释比例 |
WB 1:200-2000. IHC 1:50-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
92kDa |
Gene ID |
976 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human CD97 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human CD97 |
Subcellular Locations |
Cell membrane Multi-pass membrane protein Secreted extracellular space |
Swiss Prot |
P48960 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. |