Anti-PSMF1 Polyclonal Antibody
品牌：solarbio | 货号：K004058P
| 英文名称 | Anti-PSMF1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PI31 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 30kDa |
| Gene ID | 9491 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PSMF1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PSMF1 |
| Subcellular Locations | Cytoplasm Endoplasmic reticulum |
| Swiss Prot | Q92530 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene. |