Anti-ELAC2 Polyclonal Antibody
品牌：solarbio | 货号：K007028P
| 英文名称 | Anti-ELAC2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ELC2;HPC2;COXPD17 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 92kDa |
| Gene ID | 60528 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ELAC2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ELAC2 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q9BQ52 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3′ trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. |