Anti-VECadherin Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-VECadherin Polyclonal Antibody

品牌:solarbio | 货号:K106472P

英文名称 Anti-VECadherin Polyclonal Antibody
宿主 Rabbit
别名 Cadherin-5;CD144;Cdh5;Vascular endothelial cadherin
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量 75kDa
Gene ID 12562
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human VECadherin
性状 液体
Public Immunogen Range A synthetic peptide of human VECadherin
Subcellular Locations Cell junction Cell membrane
Swiss Prot P55284
克隆类型 Polyclonal Antibody
背景资料 This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined.