Anti-VECadherin Polyclonal Antibody
品牌:solarbio | 货号:K106472P
英文名称 |
Anti-VECadherin Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
Cadherin-5;CD144;Cdh5;Vascular endothelial cadherin |
应用 |
WB |
稀释比例 |
WB 1:3000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
75kDa |
Gene ID |
12562 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human VECadherin |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human VECadherin |
Subcellular Locations |
Cell junction Cell membrane |
Swiss Prot |
P55284 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. |