Anti-UMPS Polyclonal Antibody
品牌：solarbio | 货号：K004036P
| 英文名称 | Anti-UMPS Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | OPRT |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 52kDa |
| Gene ID | 7372 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human UMPS |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human UMPS |
| Subcellular Locations | Cytosol Nucleus |
| Swiss Prot | P11172 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a uridine 5′-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5′-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5′-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. |