Anti-FLT1 Polyclonal Antibody
品牌：solarbio | 货号：K007350P
| 英文名称 | Anti-FLT1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | FLT;FLT-1;VEGFR1;VEGFR-1 |
| 应用 | IF |
| 稀释比例 | IF 1:100-500. |
| 交叉反应 | Human |
| 蛋白分子量 | 150kDa |
| Gene ID | 2321 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human FLT1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human FLT1 |
| Subcellular Locations | Plasma membrane Endosome secreted Cytoplasm |
| Swiss Prot | P17948 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia. |