Anti-LIMS1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-LIMS1 Polyclonal Antibody

品牌:solarbio | 货号:K007093P

英文名称 Anti-LIMS1 Polyclonal Antibody
宿主 Rabbit
别名 PINCH;PINCH1;PINCH-1
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse
蛋白分子量 37kDa
Gene ID 3987
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human LIMS1
性状 液体
Public Immunogen Range Recombinant protein of human LIMS1
Subcellular Locations Cytoplasm
Swiss Prot P48059
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.