Anti-LIMS1 Polyclonal Antibody
品牌：solarbio | 货号：K007093P
| 英文名称 | Anti-LIMS1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PINCH;PINCH1;PINCH-1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 37kDa |
| Gene ID | 3987 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human LIMS1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human LIMS1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P48059 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. |