Anti-SEPT7 Polyclonal Antibody
品牌：solarbio | 货号：K004841P
| 英文名称 | Anti-SEPT7 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CDC10;CDC3;NBLA02942;SEPT7A |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 51kDa |
| Gene ID | 989 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SEPT7 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SEPT7 |
| Subcellular Locations | Chromosome Cleavage furrow Cytoplasm Midbody centromere cilium axoneme cytoskeleton kinetochore spindle |
| Swiss Prot | Q16181 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. |