Anti-PTPN3 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-PTPN3 Polyclonal Antibody

品牌:solarbio | 货号:K004495P

英文名称 Anti-PTPN3 Polyclonal Antibody
宿主 Rabbit
别名 PTP-H1;PTPH1
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 104kDa
Gene ID 5774
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human PTPN3
性状 液体
Public Immunogen Range Recombinant protein of human PTPN3
Subcellular Locations Cell membrane Cytoplasm Cytoplasmic side Peripheral membrane protein cytoskeleton
Swiss Prot P26045
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.