Anti-PTPN3 Polyclonal Antibody
品牌：solarbio | 货号：K004495P
| 英文名称 | Anti-PTPN3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PTP-H1;PTPH1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 104kDa |
| Gene ID | 5774 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PTPN3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PTPN3 |
| Subcellular Locations | Cell membrane Cytoplasm Cytoplasmic side Peripheral membrane protein cytoskeleton |
| Swiss Prot | P26045 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. |