Anti-EHMT1 Polyclonal Antibody
品牌:solarbio | 货号:K005888P
英文名称 |
Anti-EHMT1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
EUHMTASE1;Eu-HMTase1;FP13812;GLP;GLP1;KMT1D;bA188C12.1 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
141kDa |
Gene ID |
79813 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human EHMT1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human EHMT1 |
Subcellular Locations |
Chromosome Nucleus |
Swiss Prot |
Q9H9B1 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants. |