Anti-FBXO22 Polyclonal Antibody
品牌：solarbio | 货号：K005788P
| 英文名称 | Anti-FBXO22 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | FBX22;FISTC1 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human |
| 蛋白分子量 | 45kDa |
| Gene ID | 26263 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human FBXO22 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human FBXO22 |
| Subcellular Locations | Cytoplasm Z line myofibril sarcomere |
| Swiss Prot | Q8NEZ5 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants. |