Anti-AMIGO2 Polyclonal Antibody
品牌：solarbio | 货号：K006900P
| 英文名称 | Anti-AMIGO2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ALI1;DEGA;AMIGO-2 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 58kDa |
| Gene ID | 347902 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human AMIGO2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human AMIGO2 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q86SJ2 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO-1, AMIGO-2 and AMIGO-3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO-1, also designated Alivin-2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO-2 (Alivin-1) is crucial for depolarization-dependent survival. Similar to AMIGO-1 and AMIGO-2, AMIGO-3 (Alivin-3) plays a role in homophilic and/or heterophilic cell-cell interaction and signal transduction |