Anti-AMIGO2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-AMIGO2 Polyclonal Antibody

品牌:solarbio | 货号:K006900P

英文名称 Anti-AMIGO2 Polyclonal Antibody
宿主 Rabbit
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 58kDa
Gene ID 347902
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human AMIGO2
性状 液体
Public Immunogen Range Recombinant protein of human AMIGO2
Subcellular Locations Cytoplasm Nucleus
Swiss Prot Q86SJ2
克隆类型 Polyclonal Antibody
背景资料 The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO-1, AMIGO-2 and AMIGO-3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO-1, also designated Alivin-2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO-2 (Alivin-1) is crucial for depolarization-dependent survival. Similar to AMIGO-1 and AMIGO-2, AMIGO-3 (Alivin-3) plays a role in homophilic and/or heterophilic cell-cell interaction and signal transduction