Anti-SGCE Polyclonal Antibody
品牌:solarbio | 货号:K003915P
英文名称 |
Anti-SGCE Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
DYT11;ESG;epsilon-SG |
应用 |
WB IHC IF |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
交叉反应 |
Human Mouse |
蛋白分子量 |
50kDa |
Gene ID |
8910 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human SGCE |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human SGCE |
Subcellular Locations |
Cell membrane Cell projection Cytoplasm Golgi apparatus Single-pass membrane protein cytoskeleton dendrite sarcolemma |
Swiss Prot |
O43556 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A pseudogene associated with this gene is located on chromosome 2. |