Anti-UPF2 Polyclonal Antibody
品牌：solarbio | 货号：K005004P
| 英文名称 | Anti-UPF2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HUPF2;RENT2;smg-3 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 148kDa |
| Gene ID | 26019 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human UPF2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human UPF2 |
| Subcellular Locations | Cytoplasm perinuclear region |
| Swiss Prot | Q9HAU5 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein. |