Anti-HNF1A Polyclonal Antibody
品牌:solarbio | 货号:K007901P
英文名称 |
Anti-HNF1A Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
HNF1;LFB1;TCF1;MODY3;TCF-1;HNF-1A;IDDM20 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:25-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
67kDa |
Gene ID |
6927 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human HNF1A |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human HNF1A |
Subcellular Locations |
Nucleus |
Swiss Prot |
P20823 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5′-GTTAATNATTAAC-3′. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. |