Anti-PRKAG1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-PRKAG1 Polyclonal Antibody

品牌:solarbio | 货号:K008302P

英文名称 Anti-PRKAG1 Polyclonal Antibody
宿主 Rabbit
别名 AMPKG
应用 WB
稀释比例 WB 1:200-1000.
交叉反应 Human Mouse Rat
蛋白分子量 38kDa
Gene ID 5571
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human PRKAG1
性状 液体
Public Immunogen Range Recombinant protein of human PRKAG1
Swiss Prot P54619
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.