Anti-ICAM1 Polyclonal Antibody
品牌:solarbio | 货号:K008365P
英文名称 |
Anti-ICAM1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
BB2;CD54;P3.58 |
应用 |
WB IHC |
稀释比例 |
WB 1:1000-5000. IHC 1:50-200. |
交叉反应 |
Human |
蛋白分子量 |
58kDa |
Gene ID |
3383 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ICAM1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ICAM1 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P05362 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |