Anti-ICAM1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ICAM1 Polyclonal Antibody

品牌:solarbio | 货号:K008365P

英文名称 Anti-ICAM1 Polyclonal Antibody
宿主 Rabbit
别名 BB2;CD54;P3.58
应用 WB IHC
稀释比例 WB 1:1000-5000. IHC 1:50-200.
交叉反应 Human
蛋白分子量 58kDa
Gene ID 3383
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human ICAM1
性状 液体
Public Immunogen Range Recombinant protein of human ICAM1
Subcellular Locations Cytoplasm
Swiss Prot P05362
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.