Anti-TNK2 Polyclonal Antibody
品牌:solarbio | 货号:K008374P
英文名称 |
Anti-TNK2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ACK;ACK1;Tyrosine kinase non receptor 2 |
应用 |
WB IHC |
稀释比例 |
WB 1:1000-5000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
119kDa |
Gene ID |
10188 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human TNK2 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human TNK2 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q07912 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. |