Anti-MBP Polyclonal?Antibody
品牌：solarbio | 货号：K009387P
| 英文名称 | Anti-MBP Polyclonal?Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | Myelin Basic Protein;Myelin basic protien;GDB;Golli MBP;Hemopoietic MBP;HMBPR;HUGO;MBP;MGC99675;MLD;Myelin A1 Protein;Myelin Deficient;Myelin Membrane Encephalitogenic Protein;SHI;Shiverer;SP |
| 应用 | WB ELISA IHC-P IHC-F Flow-Cyt IF |
| 稀释比例 | WB 1:500-2000.?ELISA 1:500-1000.?IHC-P 1:400-800.?IHC-F 1:400-800.?Flow-Cyt 1ug/test.?IF 1:100-500? |
| 交叉反应 | Human?Mouse?Rat?Pig |
| 蛋白分子量 | 33kDa |
| Gene ID | 100731253 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of Gpig MOG |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of Gpig MOG |
| Subcellular Locations | Nucleus Cytomembrane |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function. |