Anti-COX4I1 Polyclonal Antibody
品牌：solarbio | 货号：K004618P
| 英文名称 | Anti-COX4I1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | COX IV-1;COX4;COX4-1;COXIV;COXIV-1 |
| 应用 | WB IHC IF IP |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. IP 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 20kDa |
| Gene ID | 1327 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human COX4I1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human COX4I1 |
| Subcellular Locations | Mitochondrion inner membrane |
| Swiss Prot | P13073 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3′ of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms. |