Anti-CDK5 Polyclonal Antibody
品牌：solarbio | 货号：K004169P
| 英文名称 | Anti-CDK5 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | LIS7;PSSALRE |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:10-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 33kDa |
| Gene ID | 1020 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CDK5 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CDK5 |
| Subcellular Locations | Cell junction Cell membrane Cell projection Cytoplasm Nucleus Perikaryon Peripheral membrane protein growth cone lamellipodium postsynaptic cell membrane postsynaptic density synapse |
| Swiss Prot | Q00535 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. |