Anti-PSMB8 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-PSMB8 Polyclonal Antibody

品牌:solarbio | 货号:K005186P

英文名称 Anti-PSMB8 Polyclonal Antibody
宿主 Rabbit
别名 ALDD;D6S216;D6S216E;JMP;LMP7;NKJO;PSMB5i;RING10
应用 WB IHC IF
稀释比例 WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 30kDa
Gene ID 5696
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human PSMB8
性状 液体
Public Immunogen Range Recombinant protein of human PSMB8
Subcellular Locations Cytoplasm Nucleus
Swiss Prot P28062
克隆类型 Polyclonal Antibody
背景资料 The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit.