Anti-CTCFL Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CTCFL Polyclonal Antibody

品牌:solarbio | 货号:K004348P

英文名称 Anti-CTCFL Polyclonal Antibody
宿主 Rabbit
别名 BORIS;CT27;CTCF-T;HMGB1L1;dJ579F20.2
应用 WB IF
稀释比例 WB 1:500-2000. IF 1:20-100.
交叉反应 Human Mouse Rat
蛋白分子量 76kDa
Gene ID 140690
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human CTCFL
性状 液体
Public Immunogen Range Recombinant protein of human CTCFL
Subcellular Locations Cytoplasm Nucleus
Swiss Prot Q8NI51
克隆类型 Polyclonal Antibody
背景资料 CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.