Anti-CTCFL Polyclonal Antibody
品牌:solarbio | 货号:K004348P
英文名称 |
Anti-CTCFL Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
BORIS;CT27;CTCF-T;HMGB1L1;dJ579F20.2 |
应用 |
WB IF |
稀释比例 |
WB 1:500-2000. IF 1:20-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
76kDa |
Gene ID |
140690 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human CTCFL |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human CTCFL |
Subcellular Locations |
Cytoplasm Nucleus |
Swiss Prot |
Q8NI51 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |