Anti-GZMB Polyclonal Antibody
品牌:solarbio | 货号:K003416P
英文名称 |
Anti-GZMB Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
C11;CCPI;CGL-1;CGL1;CSP-B;CSPB;CTLA1;CTSGL1;HLP;SECT |
应用 |
WB IHC IF |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
交叉反应 |
Human Mouse |
蛋白分子量 |
28kDa |
Gene ID |
3002 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human GZMB |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human GZMB |
Subcellular Locations |
Cytoplasmic granule |
Swiss Prot |
P10144 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. |