Anti-EPOR Polyclonal Antibody
品牌：solarbio | 货号：K003532P
| 英文名称 | Anti-EPOR Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | EPO-R |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 55kDa |
| Gene ID | 2057 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human EPOR |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human EPOR |
| Subcellular Locations | Cell membrane Secreted Single-pass type I membrane protein |
| Swiss Prot | P19235 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants. |