Anti-EPOR Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-EPOR Polyclonal Antibody

品牌:solarbio | 货号:K003532P

英文名称 Anti-EPOR Polyclonal Antibody
宿主 Rabbit
别名 EPO-R
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 55kDa
Gene ID 2057
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human EPOR
性状 液体
Public Immunogen Range Recombinant protein of human EPOR
Subcellular Locations Cell membrane Secreted Single-pass type I membrane protein
Swiss Prot P19235
克隆类型 Polyclonal Antibody
背景资料 This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.