Anti-PRDX3 Polyclonal Antibody
品牌:solarbio | 货号:K003581P
英文名称 |
Anti-PRDX3 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
AOP-1;AOP1;HBC189;MER5;PRO1748;SP-22;prx-III |
应用 |
WB IHC IF |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
28kDa |
Gene ID |
10935 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human PRDX3 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human PRDX3 |
Subcellular Locations |
Mitochondrion |
Swiss Prot |
P30048 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22. |