Anti-TNFAIP6 Polyclonal Antibody
品牌:solarbio | 货号:K004512P
英文名称 |
Anti-TNFAIP6 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
TSG-6;TSG6 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
31kDa |
Gene ID |
7130 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human TNFAIP6 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human TNFAIP6 |
Subcellular Locations |
secreted |
Swiss Prot |
P98066 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis. |