Anti-PPAN Polyclonal Antibody
品牌:solarbio | 货号:K005217P
英文名称 |
Anti-PPAN Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
BXDC3;SSF;SSF-1;SSF1;SSF2 |
应用 |
WB IHC IF |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
交叉反应 |
Human Mouse |
蛋白分子量 |
53kDa |
Gene ID |
56342 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human PPAN |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human PPAN |
Subcellular Locations |
Nucleus nucleolus |
Swiss Prot |
Q9NQ55 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation. |