Anti-HNRNPK Polyclonal Antibody
品牌:solarbio | 货号:K106976P
英文名称 |
Anti-HNRNPK Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CSBP;hnRNP K;HNRNPK;HNRPK;TUNP |
应用 |
IHC |
稀释比例 |
IHC 1:50-200. |
交叉反应 |
Human |
蛋白分子量 |
51kDa |
Gene ID |
3190 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human HNRNPK |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human HNRNPK |
Subcellular Locations |
Nucleus Cytoplasm |
Swiss Prot |
P61978? |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized.? |