Anti-Tbx21 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-Tbx21 Polyclonal Antibody

品牌:solarbio | 货号:K106901P

英文名称 Anti-Tbx21 Polyclonal Antibody
宿主 Rabbit
别名 TBET;TBLYM;T-box protein 21;Transcription factor TBLYM
应用 WB IHC
稀释比例 WB 1:5000-8000. IHC 1:50-200.
交叉反应 Human Mouse
蛋白分子量 58kDa
Gene ID 30009
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human Tbx21
性状 液体
Public Immunogen Range A synthetic peptide of human Tbx21
Subcellular Locations Nucleus Cytoplasm
Swiss Prot Q9UL17
克隆类型 Polyclonal Antibody
背景资料 Lineage-defining transcription factor which initiates Th1 lineage development from naive Th precursor cells both by activating Th1 genetic programs and by repressing the opposing Th2 and Th17 genetic programs . Activates transcription of a set of genes important for Th1 cell function, including those encoding IFN-gamma and the chemokine receptor CXCR3. Activates IFNG and CXCR3 genes in part by recruiting chromatin remodeling complexes including KDM6B, a SMARCA4-containing SWI/SNF-complex, and an H3K4me2-methyltransferase complex to their promoters and all of these complexes serve to establish a more permissive chromatin state conducive with transcriptional activation (By similarity).?