Anti-Tbx21 Polyclonal Antibody
品牌：solarbio | 货号：K106901P
| 英文名称 | Anti-Tbx21 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | TBET;TBLYM;T-box protein 21;Transcription factor TBLYM |
| 应用 | WB IHC |
| 稀释比例 | WB 1:5000-8000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 58kDa |
| Gene ID | 30009 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human Tbx21 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human Tbx21 |
| Subcellular Locations | Nucleus Cytoplasm |
| Swiss Prot | Q9UL17 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Lineage-defining transcription factor which initiates Th1 lineage development from naive Th precursor cells both by activating Th1 genetic programs and by repressing the opposing Th2 and Th17 genetic programs . Activates transcription of a set of genes important for Th1 cell function, including those encoding IFN-gamma and the chemokine receptor CXCR3. Activates IFNG and CXCR3 genes in part by recruiting chromatin remodeling complexes including KDM6B, a SMARCA4-containing SWI/SNF-complex, and an H3K4me2-methyltransferase complex to their promoters and all of these complexes serve to establish a more permissive chromatin state conducive with transcriptional activation (By similarity).? |