Anti-LYRIC Polyclonal Antibody
品牌:solarbio | 货号:K106879P
英文名称 |
Anti-LYRIC Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
MTDH;3D3;AEG-1;AEG1;LYRIC/3D3;metadherin |
应用 |
IHC |
稀释比例 |
IHC 1:25-100. |
交叉反应 |
Human |
蛋白分子量 |
64kDa |
Gene ID |
92140 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human LYRIC |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human LYRIC |
Subcellular Locations |
Extracellular matrix Secreted |
Swiss Prot |
Q86UE4 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance. |