Anti-NR3C2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-NR3C2 Polyclonal Antibody

品牌:solarbio | 货号:K106612P

英文名称 Anti-NR3C2 Polyclonal Antibody
宿主 Rabbit
别名 MCR;MLR;MR;NR3C2VIT
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse
蛋白分子量 107kDa
Gene ID 4306
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human NR3C2
性状 液体
Public Immunogen Range A synthetic peptide of human NR3C2
Subcellular Locations Cytoplasm Nucleus
Swiss Prot P08235
克隆类型 Polyclonal Antibody
背景资料 This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.